Deregulation of Interferon Signaling in Malignant Cells
Interferons (IFNs) are a family of cytokines with potent antiproliferative, antiviral, and immunomodulatory properties.Much has been learned about IFNs and IFN-activated signaling cascades over the last 50 Hammock years.Due to their potent antitumor effects in vitro and in vivo, recombinant IFNs have been used extensively over the years, alone or i